Summary: De novo genome assembly is a fundamental problem in computational molecular biology that aims to reconstruct an unknown genome sequence from a set of short DNA sequences (or reads) obtained from the genome.The relative ordering of the reads along the target genome is not known a priori, which is one of the main contributors to the increase
Tumor mutation burden (TMB) is a widely recognized stratification biomarker for predicting the efficacy Double clip of immunotherapy; however, the number and universal definition of the categorizing thresholds remain debatable due to the multifaceted nature of efficacy and the imprecision of TMB measurements.We proposed a minimal joint p-value crit
The article describes the macro-concepts Rod (a Slavic female deity) and Makosh (a Slavic female deity) in the Russian linguistic culture.It is the first attempt to analyze these macro-concepts in terms of conceptual Cosmetic Bag signs.The authors studied the lexemes of Rod and Makosh / Mokosh as the main representatives of the macro-concepts in th